Abstract
A mathematical model is proposed for the relationship between the bacterial cell processes resulting in the initiation of DNA replication that are responsible for DNA and protein synthesis. It is assumed that one or several precursors of DNA synthesis act as a trigger for the replication system of both the bacterial and episomal DNA present. By mathematical analysis it is shown that this model yields a stable cell cycle with a regulated cell volume at the time of intiation of DNA replication. Some proposals resulting from the model are experimentally proved with E. coli strains lysogenic for the γ bacteriophage, the DNA of which is an example of episomal DNA. The initiation timing of phage DNA replication is in accordance with the model, in that the mode and duration of inhibition of bacterial DNA replication causes the accumulation of DNA precursors leading to the initiation of replication of bacterial and episomal DNA.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
