Abstract

This paper presents a MATLAB-based simulator for the study of process control of fed-batch yeast fermentations that meets the educational needs of undergraduate and graduate students. Against the background of challenges in interdisciplinary education, the paper examines the evolving environment of simulation tools in the field of bioprocesses. It emphasizes the need for interdisciplinarity to prepare students for the complexities of the modern biotechnology industry. Built with accessibility and flexibility in mind, the simulator offers a modular structure with a graphical user interface (GUI) for novice users and direct access to MATLAB functions for advanced users. This design choice ensures ease of use for students with different programming backgrounds and allows for adaptability to alternative software environments. The introductory sections provide a detailed overview of the simulator development, including the mathematical models that govern biomass growth kinetics, mass transfer, and process quality indicators. Selected process control strategies such as rule-based and feedforward approaches are incorporated in the simulator to enhance the learning experience by allowing students to experiment with different scenarios. The paper concludes by emphasizing the simulator's adaptability, modularity, and user-friendly interface as a valuable asset in educating students about the complexities of bioprocess control.

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