Abstract

Tumor-associated antigens (TAA) produced by a tumor have been shown to inhibit the antitumor cytotoxic activity of lymphocytes and other cells. Their presence however also promises to be a tool for detection and evaluation. This model attempts to relate tumor mass, soluble TAA released from tumor cells, and the effect of cytotoxic cells on the tumor, for the purpose of improving the clinical effectiveness for quantitative assays of TAA.

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