Abstract

Purpose: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) remains an emerging disease threat, with regular reports of human cases on the Arabian Peninsula, driven by recurring camel-to-human transmission events. A prophylactic vaccine under development has been found to greatly reduce shedding in dromedaries, but there are major gaps in our quantitative understanding of the epidemiology of MERS-CoV in dromedary populations. The purpose of our work is to develop a mathematical model of MERS-CoV transmission in camels in order to address these gaps and to eventually inform the development of evidence-based animal vaccination strategies.

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