Abstract

Real innovations in medicine and science are historic and singular; the stories behind each occurrence are precious. At Molecular Medicine we have established the Anthony Cerami Award in Translational Medicine to document and preserve these histories. The monographs recount the seminal events as told in the voice of the original investigators who provided the crucial early insight. These essays capture the essence of discovery, chronicling the birth of ideas that created new fields of research; and launched trajectories that persisted and ultimately influenced how disease is prevented, diagnosed, and treated. In this volume, the Cerami Award Monograph is by Lawrence Steinman, MD, of Stanford University in California. A visionary in the field of neurology, this is the story of Dr. Steinman's scientific journey.

Highlights

  • Lawrence SteinmanThe monographs recount the seminal events as told in the voice of the original investigators who provided the crucial early insight

  • Write and Communicate I think that the American public is in general rather ignorant about science, including the subjects of the brain and the immune system

  • Patients have poked fun at me, asking “could I be one of your experimental animals that was cured of EAE?” I really take these comments to heart

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Summary

Lawrence Steinman

The monographs recount the seminal events as told in the voice of the original investigators who provided the crucial early insight These essays capture the essence of discovery, chronicling the birth of ideas that created new fields of research; and launched trajectories that persisted and influenced how disease is prevented, diagnosed, and treated. Ruth was hospitalized in the Contagious Disease Ward of the Los Angel­es County Hospital, battling with all the might of her immune system against a polio infection in her brain and spinal cord. With this stark evidence, I did not comprehend it at the time, there was no way that “immune privilege” might exist for the brain.

LIFE IN A PRIVILEGED TIME FOR SCIENCE EDUCATION
MEDICAL SCHOOL AND POSTDOCTORAL STUDIES
EARLY YEARS ON THE STANFORD FACULTY
FURTHER RESEARCH AT THE WEIZMANN INSTITUTE
Take Discoveries Forward to the Clinic With a Team

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