Abstract

A new type of chemical analysis system with a micro-machined absorptiometric flowcell was fabricated in order to evaluate the advantages of micro total analysis systems (μ-TAS). Two micro-mixers and an absorptiometric flowcell were integrated into the one-chip device with dimensions of 24mm×10mm×2mm. This device provided high sensitivity and allowed the miniaturization of other elements such as pump, battery, and reagent's bottle. Consequently, the whole size of the analysis system with the micro-device was 203mm×86mm×76mm, which was about 1/200 of the size of commercial systems (Hitachi FIA system) at volume ratio. Total consumption of reagents for one test was around 2μL, which was about 1/250 smaller than that of the commercial one. The correlation result by using a phosphate standard solution showed good linearity and high sensitivity (0.69Abs/ppm) which was ten times larger than that of the commercial one. These results clarified that μ-TAS had the capability to be superior chemical sensing systems.

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