Abstract

Background Many study reports have associated cervical squamous intraepithelial lesion (SIL) and HIV infection [1,2]. In Tanzania, however, there are limited and conflicting published reports on the association between HIV infection and SIL [3]. A study was conducted to determine the proportion and severity of SIL in HIV-infected women attending a cervical cancer screening clinic at Kilimanjaro Christian Medical Center (KCMC) in Tanzania. A total of 214 women 18 to 60 years old, among whom 99 (46.3%) and 115 (53.7%) were HIV-seropositive and HIV-seronegative, respectively, were recruited in the study. Blood samples were taken to associate SIL and degree of HIV infection by CD4+ T lymphocyte counts. Structured questionnaires with socio-demographic characteristics were administered while cervical smears were taken from all women to determine and grade the degree of SIL. High-grade and

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