Abstract
In view of the apparent contrast in clinical symptoms between the variant form of angina pectoris and conventional effort angina and of tendency towards the decrease of heart rate at the beginning of the former attack, an entirely different mechanism was assumed between these 2 diseases. Based on this assumption, 3 patients with this disease were studied from the viewpoint of catecholamines in blood. As the result, the decrease of catecholamines in blood, especially adrenaline, immediately before and at the beginning of attack, was established. Based on this fact, the mechanism of the development of the attack of the variant form of angina pectoris was explained by the temporary state of obstruction of the large branch of the coronary artery with advanced stenosis due to the increased tonus, following the weakening of the dilation effect of the coronary artery due to decrease of blood adrenaline at rest. The mechanism of development of specific clinical symptoms might be explained too by fluctuations of catecholamines in blood due to stress such as cardiac ischemia or anginal pain.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
