Abstract

Background: There is currently no agreement on the optimal management of caesarean scar pregnancy. Caesarean scar pregnancy is currently categorised into two subtypes according to the site of implantation. This may consequently result in the difference in treatment options. However, the comparison of the success rate of each treatment option according to the subtypes has not been fully investigated.Methods: 71 patients who were treated by uterine curettage (D and C), or uterine artery embolization with curettage (UAE) or hysteroscopy in conjunction with laparoscopy between January 2016 and March 2020 were included. Data on maternal age, gestational sac age, the sac diameter, the interval between two pregnancies, the number of previous caesarean sections, amount of bleeding and β-hCG levels were collected and analysed dependent on the subtypes.Results: There was no difference in the clinical parameters of the cases who received different options of treatment, as well as no difference in the clinical parameters between type 1 and type 2 caesarean scar pregnancy. The primary success rate for type 1 caesarean scar pregnancy by D and C, or UAE, or hysteroscopy in conjunction with laparoscopy was 95, or 100 or 100%, respectively. The primary success rate for type 2 caesarean scar pregnancy by D and C, or UAE, or hysteroscopy in conjunction with laparoscopy was 27, or 67, or 95% respectively.Conclusion: Our data demonstrates that hysteroscopy in conjunction with laparoscopy for type 2 caesarean scar pregnancy was the most successful compared to other options, but for type 1 caesarean scar pregnancy, D and C could be the cost-effective option.

Highlights

  • Caesarean scar pregnancy is a relatively new type and rare form of ectopic pregnancy at the site of the scar from a previous caesarean section, resulting in implantation of a blastocyst within myometrial scar tissue in the anterior lower uterine segment [1]

  • Our data demonstrates that hysteroscopy in conjunction with laparoscopy for type 2 caesarean scar pregnancy was the most successful compared to other options, but for type 1 caesarean scar pregnancy, D and C could be the cost-effective option

  • Our findings suggest that for type 1 caesarean scar pregnancy, there was no difference in the treatment options and for type 2 caesarean scar pregnancy, hysteroscopy in conjunction with laparoscopy was the most successful

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Summary

Introduction

Caesarean scar pregnancy is a relatively new type and rare form of ectopic pregnancy at the site of the scar from a previous caesarean section, resulting in implantation of a blastocyst within myometrial scar tissue in the anterior lower uterine segment [1]. The estimated incidence of caesarean scar pregnancy is regionally dependent. A recent study reported that the estimated incidence of caesarean scar pregnancy was 1.5 per 10,000 pregnancies in the United Kingdom [2]. While a systemic review study reported that the estimated incidence of caesarean scar pregnancy was 1 per 1,800 to 2,600 pregnancies globally, which represents 6% of all ectopic pregnancies in women with prior caesarean delivery [3]. There is currently no agreement on the optimal management of caesarean scar pregnancy. Caesarean scar pregnancy is currently categorised into two subtypes according to the site of implantation. This may result in the difference in treatment options. The comparison of the success rate of each treatment option according to the subtypes has not been fully investigated

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