Abstract

Recent preparations of fibrinogen fail to show the striking transient electric birefringence properties characteristic of molecules of large axial ratio. The present results are consistent with nearly spherical particles producing little form birefringence at low fields. Transverse charge asymmetry was indicated at both high and low pH. The possibility is raised that a plasma component in former preparations acted to stabilize the elongated structure of the molecule. Previous results by electric birefringence are reviewed and discussed.

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