Abstract
Objective: To test whether the Village incidence of new cases of Motor Neurone Disease (MND) over an 8-year period, is significantly different from those in the County to serve as a pilot study to identify possible interactive multienvironmental aetiology. Design: Between September 2003-June 2011, Village MND cases were compared with the County’s in people aged >54 years. The incidence of MND was determined and Odds ratios calculated. The Village MND mortality rates were juxtaposed against England & Wales MND deaths over the period. Setting: A rural Village flanked by Electro-Magnetic-Fields (EMF) close to an active airfield. The Village population has remained relatively stable, plane-take off from the airfield is at a low angle for 3-4 miles, with radar TACAN beams pulsed every 4 seconds. Participants: General population (>54 yrs) in Village and County. Main outcome measures: Cases and deaths of MND. Results: Of the County’s 236 MND cases, 11came from the Village, equal to 1 MND case per 410 people, County rate was 1: 1,844, yielding an Odds ratio of 4.5:1. Village MND deaths compared to England & Wales gave an Odds ratio of 2.3: 1; England & Wales MND deaths were double the County’s. Conclusion: The disproportionate incidence of Village MND, with its relatively intensive exposure to EMF and petrochemicals, leads us to a speculative hypothesis of possible multi-interactive environmental influences. Despite limitations inherent in cluster studies, these indicative results suggest that a more detailed national study of geographic, occupational, life-style and family background is merited and feasible.
Highlights
There is substantial evidence that neurological morbidity and mortality is increasing in most of the ten major Western countries and not age-related [1,2,3,4]
Village Motor Neurone Disease (MND) deaths compared to England & Wales gave an Odds ratio of 2.3: 1; England & Wales MND deaths were double the County’s
One immediate problem is what is the incidence of MND? A detailed UK case study on a 3 million GP data base concluded the average for both sexes was 3.25 per 100,000, based upon 830 new cases over a 15 years period [2]
Summary
Of the County’s 236 MND cases, 11came from the Village, equal to 1 MND case per 410 people, County rate was 1: 1,844, yielding an Odds ratio of 4.5:1. Village MND deaths compared to England & Wales gave an Odds ratio of 2.3: 1; England & Wales MND deaths were double the County’s
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.