Abstract
Gray zone lymphoma (GZL) is a rare hematological malignancy known to usually occur in young men. GZL has features intermediate between diffuse large B-cell lymphoma and classical Hodgkin’s lymphoma. This case report describes a 55-years old woman with GZL. Remission was achieved through R-CHOP chemotherapy and adjuvant radiation treatment over 22 months. This case is exemplary for successful management of GZL with R-CHOP chemotherapy.
Highlights
Gray zone lymphoma (GZL) is a distinct type of B-cell lymphoma with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin’s lymphoma (HL) [1]
These immunomorphologic findings were consistent with Diffuse Large B-Cell Lymphoma (DLBCL)
Following 22 months of systemic chemotherapy with adjuvant radiation treatment, the gray zone lymphoma eventually went into remission
Summary
Gray zone lymphoma (GZL) is a distinct type of B-cell lymphoma with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin’s lymphoma (HL) [1]. GZL is extremely rare and occur mostly in young men [2]. We present a case of a middle-aged woman with GZL to add to the scant body of knowledge for this rare disease
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