Abstract
Pre-gangrene is the penultimate stage of vascular insufficiency before gangrene sets in; the term is usually applied to ischemia of lower limb. A male patient admitted with complains of severe foot pain, tenderness (2-3 months), and tingling & numbness. In a past medical history, he was suffering with hypertension (HTN) and COPD. He was taking amlodipine 5 mg tablet for HTN for daily basis. The X- ray finding shows that patients were suffering COPD. The patient is known case of COPD from last 3 year. After a diagnosis he has go through a surgery for left foot pre-gangrene (below knee amputation). During surgery general anesthetic and some post and pre-operative medication is given. During hospitalization patients taking various medications like antibiotic, bronchodilator and anti-hypertensive. Specifically in this patient amoxicillin and Clavulanic acid anti-biotic combination is used to treat gangrene.
 Keywords: Hypertension, pre-gangrene, COPD, Antibiotic, bronchodilator.
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