Abstract
Takayasu’s arteritis (TA) is a rare large-vessel vasculitis that affects large arteries, mainly the aorta and its branches. It is also called a pulseless disease because of diminished or absent pulses in the upper extremities of the patient. The coronary, pulmonary and renal arteries are also affected in the progression of the disease. The prevalence of the disease is more in Asian countries and it has unknown etiopathogenesis. Here we discuss a case of TA in a 15 y old girl who was admitted with moderate LV dysfunction. The diagnosis was carried out from the results of CT aortogram which showed stenosis of right common carotid, left subclavian, left vertebral artery, right renal artery and lower lobe pulmonary arteries and other clinical examinations. Treatment was initiated with methylprednisolone and cyclophosphamide along with symptomatic treatment. But the disease progressed with the development of complications like peripheral leg ulcers. The patient was initiated palliative care in view of altered sensorium and severe LV dysfunction, but the patient succumbed to a sudden cardiac arrest. Early identification and initiation of aggressive treatment can help in symptom-free survival.
Highlights
Takayasu’s arteritis (TA) is a rare, autoimmune, idiopathic, largevessel vasculitis that affects large arteries, mainly the aorta and its branches [1, 2]
TA has been reported from different parts of the world, but the prevalence is more in oriental countries like Japan, India, Korea and Thailand [3]
Reviews suggest that the disease is confined to the female population, but it has been reported that males are affected, but disease manifestations may vary among populations [2]
Summary
Takayasu’s arteritis (TA) is a rare, autoimmune, idiopathic, largevessel vasculitis that affects large arteries, mainly the aorta and its branches [1, 2]. We report a case of 15 y old girl who was referred to our hospital for Left Ventricular (LV) dysfunction evaluation. There was a history of on and off aching pain in the left upper limb She had an episode of syncope during her exams which was again thought to be due to anxiety. No family history of cardiovascular diseases was documented She was referred to our hospital for evaluation of LV dysfunction. Ophthalmic evaluation was suggestive of grade 1-2 hypertensive retinopathy Considering these findings, the diagnosis was made as TA with the involvement of pulmonary arteries. She underwent stenting of a left renal artery in view of severe hypertension and uncontrolled LV dysfunction. The patient succumbed to a sudden cardiac arrest one year after diagnosis
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Pharmacy and Pharmaceutical Sciences
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
