Abstract
A case of vitiligo with hypertrophic lichen planus – an autoimmune association
Highlights
Amyloidosis is a rare disorder characterized by the deposition of insoluble proteins in tissues
We describe the case of systemic amyloidosis with atypical presentation
A 57-year-old patient with no significant pathological history has been followed for two months for multiple myeloma retained on the presence of medullary plasmocytosis, monoclonal gammopathy type Lambda and two CRAB criteria (Hypercalcemia, renal failure, anemia
Summary
Amyloidosis is a rare disorder characterized by the deposition of insoluble proteins in tissues. Our patient was placed under a chemotherapy regimen Cylclophosphamide-Dexamethazone-Thalidomide (CDT), associated with bisphosphonates He presented ten days after diagnosing his myeloma a medullary compression treated surgically and whose histopathological study had found asclerogenic fibrosis without individualized plasmocytic elements in the bone and cartilaginous tissues. He has reported for 20 days the appearance of some skin lesions slightly pruriginous sitting in the genital area. Once the diagnosis of nodular skin amyloidosis is retained, anamnesis, a complete clinical examination, as well as a serum electrophoresis and urinary proteins, ASGB, rectal or abdominal fat biopsy must be performed In order to exclude an amyloid deposit at the extracutaneous level [1]. Patient gave written consent to the examination and biopsy after having been informed about the procedure
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