Abstract

Hypokalemic periodic paralysis is an uncommon manifestation of thyrotoxicosis and the condition is most commonly reported in young Asian men. Patient often presents with acute onset symmetrical flaccid muscle paralysis and proximal limb muscles may be more severely involved compared to distal muscles. Thyroid swelling as well as features of thyrotoxicosis may not be overt. A very high index of suspicion is often required for the diagnosis of thyrotoxic periodic paralysis. Treatment of throtoxicosis prevents further episodes of paralysis. We report a case of thyrotoxic periodic paralysis in a young male.Bangladesh Journal of Medical Science Vol. 12 No. 03 July ’13 Page 320-321 DOI: http://dx.doi.org/10.3329/bjms.v12i3.12719

Highlights

  • Periodic paralyses refer to a heterogeneous group of muscle diseases characterized by episodes of flaccid muscle weakness occurring at irregular intervals

  • We here report a case of thyrotoxic periodic paralysis in a young male

  • In Chinese and Japanese people with hyperthyroidism, 1.8–1.9% experience TPP in contrast to North America, where studies report a rate of 0.1–0.2%.(1) The condition typically affects males and the age of onset is typically between 20 - 40years.(1) Various genetic mutations have been demonstrated in patients with thyrotoxic periodic paralysis

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Summary

Introduction

Introduction Periodic paralyses refer to a heterogeneous group of muscle diseases characterized by episodes of flaccid muscle weakness occurring at irregular intervals. Thyrotoxic periodic paralysis an uncommon manifestation of thyrotoxicosis is an acquired form of periodic paralyses. We here report a case of thyrotoxic periodic paralysis in a young male. Case Report 29 year old male patient presented to casualty with weakness of limbs more involving the lower limb of 6 hours duration.

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