A case of multisystem inflammatory syndrome in children associated with coronavirus disease 2019, presenting as unremitting fever, vomiting, and rash

Abstract

Multisystem inflammatory syndrome in children, a hyper inflammation syndrome induced by severe acute respiratory syndrome coronavirus 2, may show a fatal progression. Thus, it is important to recognize its symptoms, and provide appropriate treatment at an early stage. We report a 7-year-old boy who presented with unremitted fever, vomiting, and whole-body polymorphic rash. Laboratory findings showed lymphopenia, and elevated erythrocyte sedimentation rate, C-reactive protein, fibrinogen, d-dimer, ferritin, and triglyceride. The boy had negative findings of viruses-related to respiratory disease and meningitis, and positivity for immunoglobulin G against severe acute respiratory syndrome coronavirus 2. He was diagnosed as multisystem inflammatory syndrome in children, and received supportive care, intravenous immunoglobulin, and steroid. He was discharged without complication on day 12.