Abstract
Background: Molar-Incisor Hypomineralization (MIH) is a common childhood dental pathology. This paper describes a case with familial involvement and environmental risk factors. Case Description: A 35-year old female has yellowish-brown opacities present on central and lateral maxillary incisors, right and left maxillary canines, right and left maxillary first molars, and right and left maxillary second molars. A 33-year old male sibling has yellowish-brown opacities on the right and left central and lateral maxillary incisors. The male sibling’s fraternal twin does not have evidence of MIH. A maternal grandmother also had evidence of MIH, though involved teeth are not known. Practical Implications: MIH is a condition with both genetic and environmental components. Practitioners should consider both etiologies when patients present with the condition.
Highlights
Molar-‐Incisor Hypominer-‐ alization (MIH) is diagnosed by the presence of yellowish-‐brown or white/cream enamel opacities [1]
We-‐ erheijm et al suggested the term “Molar-‐Incisor Hypomineraliza1on (MIH)” and the attendant defini-‐ tion: “hypomineralization of sys-‐ temic origin of 1-‐4 first permanent molars (FPM), frequent-‐ ly associated with affected inci-‐ sors”[2]
The history of MIH is ob-‐ fuscated by the lack of standard-‐ ized naming before 2001 [1,6]
Summary
Molar-‐Incisor Hypominer-‐ alization (MIH) is diagnosed by the presence of yellowish-‐brown or white/cream enamel opacities [1]. Prior to 2001, the nomenclature of MIH was not standardized [1]. Other terms for this condition in-‐ cluded: hypomineralized first permanent molars (FPM), idio-‐ pathic enamel hypomineralisation in non-‐fluoride, hypomineraliza-‐ tion in FPM, and cheese molars [1]. These names were eventually subsumed under Molar-‐Incisor Hypomineralization (MIH). Some evi-‐ dence for differing rates of MIH in the mandible and maxilla has been found, but studies do not agree on which location is more common [1]. There does not appear to be a significant difference in MIH instances between the sexes [1]
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