Abstract

Here, we report a case of lung adenocarcinoma resistant to crizotinib harboring KRAS mutation and the echinoderm microtubule-associated protein-like 4 ( EML4 )-anaplastic lymphoma kinase ( ALK ) fusion gene. Our case suggests that KRAS mutation in addition to EML4-ALK fusion gene may cause the resistance to crizotinib. J Med Cases. 2014;5(12):631-633 doi: http://dx.doi.org/10.14740/jmc1985w

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