Abstract
One case of 54 years old female patient was admitted to hospital due to vomiting and diarrhea for 3 days and abnormal renal function for 1 day. The patient appeared repeatedly vomiting and watery stools 6 hours after eating 2 grain of raw carp fish bile and gradually appeared oliguresis, whole body skin yellow dye and fever symptoms. The condition of patient had no improvement after visiting the emergency department of local county hospital. She was checked in department of nephropathy in our hospital for further diagnosis and treatment. Because the patient's condition was serious and the function of liver and kidney was damaged, diagnosed as severe multiple organ dysfunction syndrome (MODS), she was transferred to ICU rescue to protect the liver, maintain water and electrolyte balance, control blood sugar, improve the circulation and give other drug treatments and actively carry out bedside continuous renal replacement therapy. Then the body temperature and hemogram of the patients became normal, liver and kidney function improved obviously, urinary production became normal, skin yellow dye faded and vital signs became stable. The successful treatment of this patient indicated that bedside continuous renal replacement therapy can not only have a good support for the kidneys but also reduce the waterfall effect of inflammatory of patients with severe MODS, which has great therapeutic effect on the multi organ dysfunction caused by fish bile poisoning.
Highlights
Fish bile poisoning refers to acute poisoning caused by eating raw fish bile
There was a significant increase in the level of aminotransferase and bilirubin, and the liver function injury showed systemic jaundice.At the same time, there was a significant increase in serum creatinine and urea nitrogen, and the renal dysfunction showed oliguresis
In many cases of eating raw fish bile poisoning can lead to increasing of BUN, showed: creatinine (Scr), ALT and AST, which can lead to acute liver and renal function damage, and even multiple organ dysfunction syndrome (MODS) [7]
Summary
Fish bile poisoning refers to acute poisoning caused by eating raw fish bile. Because the raw fish gall contains bile salt and cyanide and other ingredients which can inhibit cytochrome oxidase, mitochondrial function is inhibited. 1 cases of patient with multiple organ dysfunction syndrome (acute liver and kidney injury) due to eating raw carp bile were treated in our department. Fish bile poisoning complicated with multiple organ dysfunction: Acute liver and kidney injury.
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