Abstract
The optoelectronic sensor OPT101 have merits in advanced optoelectronic response characteristics at wavelength range for medical near-infrared spectroscopy and small-size chip design with build-in trans-impedance amplifier. Our lab is devoted to developing a series of portable near-infrared spectroscopy (NIRS) devices embedded with OPT101 for applications in intensive care unit clinics, based on NIRS principle. Here we review the characteristics and advantages of OPT101 relative to clinical NIRS instrumentation, and the most recent achievements, including early-diagnosis and therapeutic effect evaluation of thrombus, noninvasive monitoring of patients' shock severity, and fatigue evaluation. The future prospect on OPT101 improvements in noninvasive clinical applications is also discussed.
Highlights
Optoelectronic sensors have been applied in fruit or stem growth monitoring in agriculture [1], nitric oxide detection with high sensitivity [2], pulse oximetry for pulse rate and oxygenation measurement [3], and salivary diagnosis of stomach cancer [4]
With the optoelectronic detector OPT101, we innovatively developed a series of near-infrared spectroscopy (NIRS) devices for intensive care unit (ICU), including the common health scanner, the thrombus monitor, monitor for patients with shock, and the imager for fatigue evaluation
Our study on thrombus monitor showed that NIRS monitoring of ∆[HbO2 ]/∆[Hb] played a fairly sensitive role in diagnosis of thrombus, as well as the therapeutic effect tracking and evaluation
Summary
Ting Li 1,2, *, Fulin Zhong 1 , Boan Pan 1 , Zebin Li 1 , Chong Huang 3 and Zishan Deng 1.
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