Abstract
Mandibles, maxillae, and snouts (premaxillary and nasal bones) were dissected from rats suckling from dams fed a normal (25 per cent protein) diet at 3, 7, 11, 15, 19 and 23 days of age. Whole bones were cleaned, weighed, and analysed for DNA, RNA, protein and calcium. The growth trends in all three bones represented a pattern of changing biochemical events which for maxilla and snout were similar and distinct from those in the mandible. Two periods of hyperplastic growth were observed: one perinatal and the other about the time of weaning. The perinatal growth period was asynchronous between the mandible and the bones of the upper face, allowing for the possibility of differential impairment of development through environmental stress, which could result in disharmonious facial growth.
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