Abstract
A 3 × 6 arrayed charge coupled device (CCD) X‐ray detector has been developed for rapid data collection in macromolecular crystallography at Photon Factory. The total active area is 236 mm × 236 mm (76.8 μm × 76.8 μm / pixel at the input phosphor, 3072 × 3072 pixels). Each module consists of an input phosphor, a 3.2 : 1 fiber‐ optic‐taper (FOT), a CCD, and a readout circuit. The input phosphor is Gd2O2S:Tb (P‐43), which is deposited onto an aluminum coated Mylar sheet to increase the sensitivity. The outputs from eighteen (3 × 6) CCDs are readout in parallel and then are digitized by 16 bit analog‐to‐digital converters. The advantage of this detector over the conventional FOT‐coupled CCD detectors is a unique CCD readout scheme that enables us to record successive x‐ray exposures without interruption among them. A shutter is not needed for CCD readout and the sample crystal can be rotated continuously without interruption during data acquisition. We have collected one data set of a Lysozyme crystal for 180 degree with 1.5 degree per slice in 360 seconds. The exposure time of each slice is 3 seconds. The duty‐ratio of the x‐ray exposure to the data collection time is 100 %. This detector combined with a synchrotron radiation source is very suitable for rapid data collection in macromolecular crystallography.
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