Abstract
Traditional delivery systems fail to provide good bioavailability of nutrients and drugs. Encapsulation of these bioactive compounds in nanodelivery systems is more effective in enhancing their bioavailability since they provide targeted and timely delivery, protection against the harsh environment of the stomach, increased solubility, and more controlled release profiles in the intestines. In this chapter, recent studies on fabrication of biobased nanodelivery systems to enhance the bioavailability of nutrients and nutraceuticals are summarized. To understand the different nanoparticulation methods and their thermodynamic mechanisms, the studies are presented in four categories: nanoprecipitation, complex coacervation, layer-by-layer assembly for spherical and tubular nanoparticles, and micro/nanoemulsification. The effects of fabrication parameters on the morphology, stability, encapsulation efficiency, and the bioavailability of nanoparticles are discussed in detail to provide a comprehensive understanding of nanodelivery systems to the readers.
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