Abstract
Dermal white adipose tissue (dWAT), a unique layer which is enriched with adipocytes, preadipocytes and adipocyte progenitors, is indispensable for maintaining skin homeostasis and tissue regeneration during skin wound healing. However, the origin, developmental path and the cellular complexity and plasticity of dWAT lineage cells remain poorly understood. Here, by single-cell RNA-seq (scRNA-seq) analyses of dermal cell populations isolated from mice at various post-developmental ages or at indicated post-wounding days, we have carried out in-depth analysis to define how dermal adipocytes are differentiated from their progenitors and to identify key signaling pathways that regulate dermal adipogenesis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
