Abstract

The prognostic factors in 100 cases of rectal adenocarcinoma curatively treated at Ankara Oncology Hospital between 1986 and 1993 were retrospectively reviewed using multivariate analysis. Age, sex, symptoms of obstruction and perforation, duration of symptoms, hemoglobin and serum albumin levels, anatomic localization, diameter and macroscopic appearance of the tumor, the type of curative surgical procedures, radical pelvic lymph node dissection, perioperative whole blood transfusion, postoperative complications, adjuvant therapy, multiple colorectal tumors, lymphatic, venous and perineural invasion, grade, lymph node metastases and stage of the disease were used as prognostic parameters. According to Kaplan Meier method five-year survival rate was 62.2%. Cox regression analysis revealed that symptoms of obstruction and perforation, annular tumors, localization, grade, perineural invasion, perirectal lymph node metastases and perioperative transfusion were dominant prognostic factors in patients with rectal carcinoma. The prognostic factors in 100 cases of rectal adenocarcinoma curatively treated at Ankara Oncology Hospital between 1986 and 1993 were retrospectively reviewed using multivariate analysis. Age, sex, symptoms of obstruction and perforation, duration of symptoms, hemoglobin and serum albumin levels, anatomic localization, diameter and macroscopic appearance of the tumor, the type of curative surgical procedures, radical pelvic lymph node dissection, perioperative whole blood transfusion, postoperative complications, adjuvant therapy, multiple colorectal tumors, lymphatic, venous and perineural invasion, grade, lymph node metastases and stage of the disease were used as prognostic parameters. According to Kaplan Meier method five-year survival rate was 62.2%. Cox regression analysis revealed that symptoms of obstruction and perforation, annular tumors, localization, grade, perineural invasion, perirectal lymph node metastases and perioperative transfusion were dominant prognostic factors in patients with rectal carcinoma.

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