Abstract
Chronic sinusitis (CRS) is characterized by chronic facial pain, pressure, headache, fatigue, and other sinus symptoms. We examined the association between psychiatric comorbidity, symptom profiles, and resource utilization in CRS. With IRB approval, this was a prospective cohort study of adults presenting for a specialist evaluation of CRS, studied with two validated instruments: the Rhinosinusitis Symptom Inventory (RSI) and the Hospital Anxiety and Depression Scale. Since the correlation between anxiety and depression is high, we used established cutoff scores to construct 3 groups, each with 3 levels of symptoms: anxiety, depression, and the combination of anxiety and depression (combined psychopathology group) into Low, Moderate, and High (sensitive and specific for a DSM depression or anxiety disorder).
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