Abstract
Graft passenger lymphocytes are known to influence auto- and allo-immune responses following transplantation. The fate of the donor passenger CD4 T cells is unclear and maybe influenced by the degree of Human Leukocyte Antigen (HLA) disparities and the natural killer (NK) cell alloreactivity. Thus, we investigated the relationship between the duration of donor CD4 T cell chimerism; the degree of HLA mismatches and NK cell alloreactivity in lung transplant recipients.
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