Abstract

associated hypoxemia, different types of MS are considered. We evaluate the outcomes in this population and the influence of the type of MS used. Methods and Materials: 101 patients presented PGD requiring MS, between 01/2000-07/2011. Intra-aortic Balloon Pump (IABP) was used in 40 cases with mild-moderate ventricular dysfunction. Extracorporeal Membrane Oxygenation (ECMO) was used in 30 cases with severe ventricular dysfunction not infrequently with associated hypoxemia. Ventricular Assist Device (VAD) was used in 19 cases (18 RVAD,1 BiVAD). Combination of ECMO after VAD (or vice-versa) was used in 12 cases (combined MS). Results: No significant donor or recipients differences were noted among the groups, except for higher age and pre-transplant pacemaker/ICD in the VAD group (p 0.04 and 0.04). 30-day and 1-year survival were 98%, 79%, 50%, 25% and 90%, 53%, 43%, 8% in the IABP, VAD, ECMO and combined MS groups respectively. Patients undergoing VAD implantation requiring also ECMO support had higher risk of mortality than those not requiring ECMO pre or post VAD implant (p 0.002). Multivariate analysis showed ECMO (alone or with VAD) (HR:11.95,95%CI:4.3532.85,p 0.0001), preoperative cardiac surgery (HR:2.46,95%CI:1.135.36,p 0.023), and diabetes (HR:2.21,95%CI:0.99-5.01,p 0.050) as risk factors of 30-day mortality.

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