Abstract
The human hair follicle (HF) contains multiple follicular melanin units (FMU) consisting of diverse subpopulations of melanocytes, defined by their location and level of differentiation/melanogenic-acitivty. This includes the infundibulum (In-FMU), stem/bulge (Stem-FMU), sebaceous gland (Sb-FMU), outer root sheath (O-FMU), peripheral proximal bulb (PP-FMU), and melanogenically-active bulb region (M-FMU). The expression of various melanogenic markers (i.e., MITF, DCT/TRP-2, Sox10, c-KIT) are said to be key features of melanocyte differentiation status.
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