Abstract
We have previously shown that short-term feeding (<1 month) with a high-sugar, moderate-fat diet (i.e., Western diet) is enough to induce clinically and molecularly-detectable psoriasiform dermatitis (PsD), suggesting that certain diet patterns could contribute to the development of PsD. However, the role of specific dietary components like sugar remains to be elucidated. Herein, we showed that short-term exposure to glucose (4 weeks) enhances the susceptibility of mice to PsD induced by imiquimod (IMQ).
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