Abstract
It is essential to devise industrial processes whereby plasmid DNA can be manufactured to meet the quality, economy, and scale requirements projected for future gene medicine and DNA vaccine production. To date, most plasmid fermentation media and processes result in low yields, imposing a cost and purity burden on commercialization of plasmid DNA production. Here we report the development of an inducible fed-batch fermentation process that dramatically increases volumetric yield and specific plasmid yield with respect to cell mass, while maintaining or enhancing plasmid integrity.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
