Abstract
Background and Aims: Diabetes mellitus increases morbidity and mortality in patients with liver cirrhosis. The aim of this study was to investigate the rate of diabetes mellitus in chronic liver diseases (chronic hepatitis, liver cirrhosis and hepatocellular cancer) and to evaluate the correlation of diabetes mellituswith the etiology and severity of liver disease. Materials and Methods: One hundred and eighty-six patients withchronic liver disease (90 chronic hepatitis, 80 cirrhosis and 16 hepatocellular carcinoma) were recruited retrospectively from January 2007 to July 2010. Based on fasting blood glucose levels, normoglycemia, impaired fasting glucose, and diabetes mellitusstates among patients were determined. Patients were evaluated by classification in terms of age, gender, and etiology, and with a diagnosis of cirrhosis and hepatocellular cancer, were additionally classified in terms of Child-Pugh and MELD (Model for End-Stage Liver Disease) scores. Results: Rates of diabetes mellitusand impaired fasting glucose among chronic liver disease patients were determined as 28% and 20.4%, respectively. Normoglycemia was significantly higher in HBV patients than in HCV, alcohol-induced chronic liver disease and cryptogenic patients (p
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