34 CORRELATION BETWEEN URIC ACID LEVEL AND ERECTILE DYSFUNCTION IN CONTROLLED HYPERTENSION MALE PATIENTS

Abstract

Background: Uric acid (UA) is considered as a marker of atherosclerosis related to endothelial dysfunction, microvascular disease, and hypertension which plays a major role in erectile dysfunction (ED) Objective: The aim of this study was to investigate whether there is correlation between UA and ED in controlled hypertension male patients Methods: This is an observational analytic study with cross sectional approach which has done in Kandou Hospital from October to December 2021. Data analysis was using SPSS 22. This study has been done in 40 to 60-year-old-males, married, alive wife, sexually active at least three months, controlled hypertension. Uric acid was measured by blood serum. Erectile dysfunction was scoring by the International Index of Erectile Function (IIEF-5) questionnaire. The exclusion criteria are acute illness, chronic kidney disease, diabetes mellitus, dyslipidemia, stroke, cancer, obesity, smoking, alcoholic, autoimmune disease, underwent urologic surgery, not taking UA-lowering-therapy in 3 months, having communication problem. Data analysis was using p<0.05 Result: There are 30 males. The age mean was 53.43 ± 7.45 years old. Uric-acid level mean was 6.84 ± 1.56 g/dl. There were 11 patients has mild-moderate ED with 7.85 ± 1.73 g/dl mean-UA level, 12 patients have mild ED with 6.58 ± 1.11 g/dl mean-UA level, and 7 patients has no ED with 5.67 ± 0.99 g/dl mean UA-level. Uric-acid level has significant negative correlation with IIEF-5 score in controlled hypertension male (r = -0.506, p = 0.004) Conclusion: There is significant correlation between UA level and IIEF-5 score in controlled hypertension male patients