33935 Comorbidities in rosacea, common origin or random chance?

Abstract

Background: It is known that rosacea’s etiology is multifactorial, even though there are mechanisms not completely elucidated. A lot of comorbidities have been described in this disease. Chronic inflammation may be an important factor explaining its association. In Colombia there are few studies describing the rosacea population. We aim to describe the comorbidities of a group of patients with rosacea in a dermatology center in Bogota, Colombia. Materials and methods: A descriptive retrospective study was performed. Data were collected from January 2014 to July 2021 in a dermatologic center in Bogota, Colombia. We recorded comorbidities and demographic variables. We used relative and absolute frequencies. Data analysis was performed in Epi-Info 7. Results: Of 1017 patients, 79.25% (n = 806) were women. Mean age was 46.12 (SD ± 17.55). The most common comorbidity was hypertension in 18.10% of patients (n = 184), followed by hypothyroidism with 11.11% (n = 113). Approximately 1 of 5 patients reported having at least 1 family member with rosacea (n = 216). Allergic rhinitis was present in 82 patients (8.06%), 7.86% (n = 80) had dyslipidemia, 6.09% (n = 62) had diabetes, 5.70% (n = 58) had rheumatologic disease, 5.50% (n = 56) had gastroesophageal reflux disease, 3.54% (n = 36) had migraine, and depression was present in 14 patients (1.38%). Other coexisting dermatoses were seborrheic dermatitis in 10.12% (n = 103) acne in 4.43% (n = 45) and atopic dermatitis in 32 patients (3.24%). Conclusions: As reported in the literature, we found that rosacea is linked to several diseases whose pathophysiology involves an inflammatory mechanism. This finding should alert dermatologists to review rosacea patients with a holistic approach.