Abstract
Introduction and aims of the study: Mucosa-associated invariant T (MAIT) cells constitute a distinct subset of T cells important in mucosal defense against bacterial infections. MAIT cells are found in the endometrial mucosa but little is known regarding human MAIT cell biology in the human uterus. Methods: We performed a high-dimensional flow cytometry characterization of endometrial MAIT (eMAIT) cells from pre- and postmenopausal women, and in decidua from first-trimester pregnancies. To assess eMAIT cell function, we stimulated isolated eMAIT cells with Neisseria gonorrhoeae (N.
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