Abstract
Currently, no objective diagnostic criteria exist for many chronic pain conditions. Chronic pelvic pain (CPP) and fibromyalgia (FM) are two chronic pain conditions that may each involve structural and functional alterations within the brain. Regional differences in gray matter (GM) density exist between various types of chronic pain and healthy volunteers. However, how these alterations in regional GM density contribute to individual types of chronic pain syndromes remains unclear. Further, the majority of previously reported findings have been obtained using conventional univariate methods, such as voxel based morphometry.
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