Abstract

The 3-dimensional (3D) printing technologies, referred to as additive manufacturing (AM) or rapid prototyping (RP), have acquired reputation over the past few years for art, architectural modeling, lightweight machines, and tissue engineering applications. Among these applications, tissue engineering field using 3D printing has attracted the attention from many researchers. 3D bioprinting has an advantage in the manufacture of a scaffold for tissue engineering applications, because of rapid-fabrication, high-precision, and customized-production, etc. In this review, we will introduce the principles and the current state of the 3D bioprinting methods. Focusing on some of studies that are being current application for biomedical and tissue engineering fields using printed 3D scaffolds.

Highlights

  • The conception of 3-dimensional (3D) printing technologies was first introduced in 1986 by Charles W

  • We describe the four different type of 3D bioprinting technology for fabrication of 3D structure and its application in tissue engineering and regenerative medicine fields

  • We will introduce the four types of 3D bioprinting methods that are most commonly used such as Stereolithography Apparatus (SLA) and Digital Light Processing (DLP) in vat photopolymerization, Fused Filament Fabrication (FFF) in material extrusion, Selective Laser Sintering (SLS) in powder bed fusion, and inkjet 3D printing in binder jetting methods

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Summary

Background

The conception of 3-dimensional (3D) printing technologies was first introduced in 1986 by Charles W. We describe the four different type of 3D bioprinting technology for fabrication of 3D structure and its application in tissue engineering and regenerative medicine fields. We will introduce the four types of 3D bioprinting methods that are most commonly used such as SLA and DLP in vat photopolymerization, FFF in material extrusion, SLS in powder bed fusion, and inkjet 3D printing in binder jetting methods. Elomaa et al showed that they used the L-alanine-derived depsipeptide to synthesize a new biodegradable, photopolymerizable poly(ethylene glycol-co-depsipeptide) macromer for the DLPbased fabrication of cell-laden hydrogel constructs for vascular applications [45] They (Elomaa et al.) reported that three-armed polycaprolactone (PCL) oligomers of various molecular weights were synthesized, end-functionalized with methacrylic anhydride and photopolymerized. The human mesenchymal stem cells on this 3D structure exhibit a characteristic of superior cell adhesion and proliferation

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