Abstract
Objective: To bring the current data of pheochromocytoma, which has a poor clinical course when diagnosed late and incorrectly, to the literature. Material and Methods: According to the retrospectively evaluated data of patients diagnosed with pheochromocytoma biochemically and pathologically, 32 patients were examined in the study, meeting the eligibility criteria. Exclusion criteria: being pregnant, being under the age of 18, only having a biochemical diagnosis and not having regular endocrinological records. The patient’s name-surname, gender, age, presence of an additional disease, clinical findings, computerized tomography (CT), magnetic resonance (MR) images, normetanephrine and metanephrine values were recorded in detail, as stated in the ethics committee approval. The results were evaluated using the Wilcoxon - T test using SPSS Statistics 25.0. Results: According to the results of 32 patients, 28 women and 4 men, the most common finding was sweating (90.6%). Tachycardia (84.4%), hypertension (84.4%), skin rash (56.6%), fatigue (75%), shortness of breath (46.9%), headache (31.3%), anxiety (31.3%), fear of death (21.9%), tremor (18.8%), pale skin (18.8%), nausea (12.5%), vomiting (9.4%), visual impairment (6.3%) and weight loss (3.1%) were determined. Locally, 43.8% of the tumors were seen on the right and 36.3% on the left. A statistically significant difference was found between preoperative and postoperative metanephrine values (p<0.05). Statistically significant difference was found between preoperative and postoperative normeta-nephrine values (p<0.05). There was no statistically significant difference between preoperative and postoperative basal cortisol values. (p=0,816). Conclusion: The current data of patients diagnosed with pheochromocytoma who applied to Izmir Katip Celebi University Ataturk Training and Research Hospital were examined and it was seen that the symptoms of these patients were correlated with patients around the world. It was concluded that preoperative and postoperative metanephrine and normetanephrine decreased significantly (p<0.05), but no significant change was observed in basal cortisol levels (p>0.05).
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