Abstract

As new COVID-19 variants emerge, it’s vital to understand how certain populations are affected. Sparse data exists on whether vaccinated patients with prior cutaneous malignancies are at higher risk for adverse events or breakthrough infections (BI) compared to the general population. Therefore, we examined the safety and efficacy of the COVID-19 vaccine in skin cancer patients. A retrospective study using TriNetX, a multicenter database of ∼80 million records, was completed. Patients who completed a mRNA COVID-19 vaccine sequence or received an additional booster were identified up to November 15th 2021 and divided into two cohorts based on history of skin cancer.

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