2263 GRAFT KIDNEY FUNCTION PREDICTION BASED ON THE RATIO OF DONATED KIDNEY VOLUME TO RECIPIENT BODY SURFACE AREA

Abstract

You have accessJournal of UrologyTransplantation & Vascular Surgery: Renal Transplantation, Vascular Surgery II1 Apr 20122263 GRAFT KIDNEY FUNCTION PREDICTION BASED ON THE RATIO OF DONATED KIDNEY VOLUME TO RECIPIENT BODY SURFACE AREA Kyung Hwa Choi, Woong Kyu Han, Seung Choul Yang, and Joon Chae Na Kyung Hwa ChoiKyung Hwa Choi Seoul, Korea, Republic of More articles by this author , Woong Kyu HanWoong Kyu Han Dallas, TX More articles by this author , Seung Choul YangSeung Choul Yang Seoul, Korea, Republic of More articles by this author , and Joon Chae NaJoon Chae Na Seoul, Korea, Republic of More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.2441AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The graft function after living kidney transplantation depends on the functioning nephron mass of donated kidney. In this study, formulas that predict the graft function after kidney transplantation are proposed using the ratio of donated kidney volume and recipient body surface area (BSA). METHODS 261 cases of living kidney transplantation between 2007 and 2009 were included in this study. In each case, preoperative 64-section helical CT scans were performed and the volume of each donated kidney was measured using the 3-dimensional reconstruction program Ripidia¢ç. To evaluate the graft function, the estimated GFR (eGFR) using the Modification of Diet in Renal Disease (MDRD) formula was calculated for each patient in the recipient group just before and 12 months after the operation. The preoperative eGFR of each donor was also calculated. The donated kidney volume, preoperative renal function, and demographic factors of each donor and recipient were evaluated as predictors. RESULTS The mean ages of the donors and recipients were 40.9 and 41.4 years. The mean donated kidney volume and donated kidney volume/recipient BSA ratio was 153.4ml and 96.9 ml/m2. The mean preoperative and postoperative eGFRs of the recipients were 8.8 and 59.5 ml/min respectively, and the mean preoperative eGFR of the donors was 92.1 ml/min. The donated kidney volume to recipient BSA ratio, donor age, and recipient gender were significant predictors for the eGFR level. From the multiple linear regression equation and predicted probability from logistic regression, the following formulas could be calculated. CONCLUSIONS With the graft kidney volume to recipient BSA ratio, donor age, and recipient gender, we could predict the graft function at 12 months after kidney transplantation. Although this study only considered the preoperative variables to serve a specific purpose, the resulting formulas can help physicians deliver the postoperative prognosis before transplantation, and also to avoid the insufficient volume donations. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e913 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information Kyung Hwa Choi Seoul, Korea, Republic of More articles by this author Woong Kyu Han Dallas, TX More articles by this author Seung Choul Yang Seoul, Korea, Republic of More articles by this author Joon Chae Na Seoul, Korea, Republic of More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...