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21 – Therapy-Associated Neuropathology

Publication Date Jan 1, 2018

Abstract

Now that post-therapy biopsies have become increasingly common, it is critical to distinguish therapy-induced changes from native pathology, including tumor necrosis, demyelination, cerebral infarction, inflammatory conditions, vasculitis, and others. The very therapies employed to enhance survival and quality of life can also be neurotoxic. Therefore this chapter highlights the diagnostic changes associated with radiation necrosis, non-necrotizing radiation injuries, therapy-induced leukoencephalopathies and vasculopathies, and secondary neoplasms after therapy.

Concepts
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Quality Of Life
Cerebral Infarction
Therapies
Radiation
Radiation Necrosis
Neoplasms
Leukoencephalopathies
Necrosis
Therapy-induced Changes
Injuries

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