Abstract

Sandmeyer reaction of 2-amino-6-methoxy (or ethoxy)-benzothiazole (I) gave the 2-chloro derivative (II) which was condensed with dimethylamine to (III) and dealkylated to 2-dimethylamino-6-hydroxybenzothiazole (IV). The accompanying table shows the comparison of the melting points of the objective compound and the intermediates obtained during the course of the present syntheses with those described in existing literature.

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