Abstract
The demographic research by R. M. Netting and W. Ellis in 1970 71, 1974 and 1977 about the relatively isolated population of Torbel (Canton of Wallis, Switzerland) offers a valuable source for a serogenetic study (blood groups, serum proteins, enzymes) and for a programme on the population genetics of this community. The historical data (since 1665) of the village represent fundamental information on the population changes (population dynamics), the familial structure of the population (pedigrees, gene pool) and its connections with other communities and valleys (migration). The blood research programme, undertaken with the collaboration of the Gerichtlich-Medizinisches Institut Zurich (H. Hartmann and M. Mahler) and the Zentrallaboratorium des Schweizerischen Roten Kreuzes Bern (R. Butler and R. Pflugshaupt), concerns seven blood groups, ten serum proteins and 17 enzymes of the red blood cells. Up to now, the research has led to the detection of some rare blood protein alleles (Gc’ c3) which are, respectively, rare phenotypes in the systems 6-PGD, Pi, Gc, C3 and Bf. Formal genetics of these rare phenotypes was done with the help of large families. Micro-evolutionary processes such as isolation, migration and genetic drift are considered as possible explanations for numerous statistically significant deviations in the allele frequencies of the Tijrbel population from other Swiss populations,
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