Abstract
Repair and regeneration of orbital wall defects still remain a challenging issue in medicine; the need to develop new biomaterials is great of importance. Although the use of autografts is considered as the golden standard, the shortage of donors limits their broad applications. Alloplasts (metals, polymers, and their composites) present a couple of advantages regarding repair and reconstruction of orbital wall defects; however, there are some critical restrictions when they implanted in the human body. Three-dimensional (3D) scaffolds made of various biomaterials offer great opportunities for improving the repair process because they can stimulate and support the growth of new healthy tissue. In this chapter, we first summarize all natural and synthetic materials used in the restoration of orbital wall defects and then discuss the usability of three-dimensional scaffolds in line with future outlooks.
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