154 Observation of Whole Digestive Tract of a Human by a Single Passage of a Self-Propelling Capsule Endoscope

Abstract

as history of small bowel surgical resection, there was a difference in orocecal transit time between the 8-hr outpatient capsule in the patient with small bowel surgery versus without (348 min vs. 310 min, p 0.0170, Mann-Whitney test). Overall, in the 12-hr capsule group 49% (53/108) were women with an average age 60 (median 65) comparable to the 8-hr group with 60% women and average age 60 (median 65). For the 12-hr group there was an overall positive finding in 10/108 (9%) beyond the 8-hour time frame, including small bowel lesions, such as angiectasias, bleeding anastomotic varices, heme at the distal small bowel, ulcerated mucosa at the terminal ileum and also outside the small bowel with heme in the colon, suggesting a missed colonic lesion or colonic ulcers in patients with IBD. Conclusions: To our knowledge this is the largest case series of 12-hour wireless capsule endoscopies to date. A 12-hour battery capsule may improve cecal intubation rate and orocecal transit time, especially in the inpatient setting. As a result, there is an increased yield in clinically relevant findings, including both heme and diagnostic lesions.