Abstract
Although epirubicin-based regimens are highly effective in breast cancer care, their cardiotoxicity may be limiting for their prescriptions. The use of left ventricular ejection fraction (LVEF) for screening of epirubicin-induced cardiotoxicity (EIC) may be too late to allow intervention and preventive measures. The aim of our study was to investigate the predictive value of 2D- Global Longitudinal Strain (GLS) to early detect EIC.
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