Abstract

Swallowing, digestion and absorption take place through the digestive or alimentary tube, a 7- to 10-meter hollow muscular conduit. The digestive process converts food material into a soluble form easy to absorb by the small intestine. The elimination of insoluble residues and other materials is the function of the large intestine. Histologically, the digestive tube consists of four major layers: (1) an inner mucosal layer encircling the lumen, (2) a submucosal layer, (3) a muscularis externa layer and (4) a serosal/adventitial layer. The inner mucosal layer shows significant variations along the digestive tube. It is subdivided into three components: (1) an epithelial layer, (2) a connective tissue lamina propria and (3) a smooth muscle muscularis mucosae. This chapter focuses on the histologic features of the oral cavity, the esophagus and the stomach with a particular emphasis on the mechanisms that affect the function of these specific segments of the alimentary system.

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