Abstract

The ESGO/ESTRO/ESP guidelines for endometrial cancer published in November 2020 in the International Journal of Gynaecological Cancer gave us a trailblazing guide to steer our wheels in the precisely carved direction for the treatment of endometrial cancer, the commander being the molecular markers(TP53, MSH6, PMS2 and POLE mutation). Since the complete molecular profiling is not feasible in a low middle income country like India we started getting the tissues of endometrial carcinoma tested for TP53 mutation because its mutation can label even a low risk disease to high risk disease, worsening the treatment outcomes.

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