Abstract

Recent data suggests that heart dose independently predicts OS after RT for non-SCLC. However, to date, limited research on the impact of cardiac dose on OS of SCLC patients has been reported, with only one paper by Ni et al. (J. Thorac. Dis. 2019) exploring this in a cohort of 18 stage III SCLC patients. Moreover, further investigations are needed to determine whether heart dose is more significant than dose to other structures local to the tumour, such as the lungs or oesophagus. In this study, we investigate the impact of heart, lung and oesophageal dosimetry on the OS of SCLC patients following chemo-RT.

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